fnctId=prof,fnctNo=119 안긴내(Ahn, Ginnae) 직위(직급) 교수 연구실 교수전공 및 연구분야 기능성식의약소재응용학 연락처 061-659-7213 이메일 gnahn@jnu.ac.kr 홈페이지 - 학력사항 - 박사: 제주대학교 해양과학대학 해양생명과학과 (2010년 8월 ) 박사논문제목: Immune activation of sulfated polysaccharide isolated from Ecklonia cava and its biological mechanism - 석사: 제주대학교 해양과학대학 해양생물공학과 (2007년 2월 ) 석사논문제목: Immunomodulatory effects of Ecklonia cava - 학사: 제주대학교 해양과학대학 해양생물공학과 (2004년 2월 ) 경력사항 - 2006년 3월 ~ 2010년 8월 : 제주대학교 해양과학대학 해양생명과학과 해양자원이용공학실험실 박사과정 연구원- 2009년 3월 ~ 2010년 8월 : 제주대학교 방사선응용과학연구소 특별연구원 - 2010년 9월 ~ 2011년 5월 : 제주대학교 수의과대학 응용세포조직학 실험실 박사후연구원 - 2011년 6월 ~ 2013년 5월 : 동경농공대학 농학부 수의학과 외국인 특별 연구원 (JSPS fellow, 일본 학술진흥회) - 2013년 6월 ~ 2013년 9월 : 동경농공대학 농학부 수의학과 산학연 특별 연구원 - 2013년 10월 ~ 2014년 2월 : 동경농공대학 농학부 수의학과 외국인 특별 연구원 (Special JSPS fellow, 일본 학술진흥회)- 2014년 3월 ~ 현재 : 전남대학교 해양바이오식품학과 부교수 연구업적 [국외논문 (SCI (E)급) (First Author)] 1. Ahn G, Hwang I, Park E, Kim J, Jeon YJ, Lee J, Park JW, Jee Y. Immunomodulatory effects of an enzymatic extract from Ecklonia cava on murine splenocytes. Mar. Biotechnol (NY). 10(3): 278-289, 2008. 2. Ahn G, Park E, Lee KW, Shin T, Park JW, Woo HC, Jeon YJ, Jee Y. Anti-inflammatory effects of enzymatic extract from Ecklonia cava on TPA-induced ear skin edema. Food Sci. Biotechnol. 17(4): 745-750, 2008. 3. Ahn G, Kim JH, Park E, Lim YK, Lee KW, Jeon YJ, Jee Y. Immunomodulatory Effects of a Methanol Extract from Opuntiaficus indica on Murine Splenocytes, Food Sci. Biotechnol. 18 (6): 1316-1321, 2009. 4. Ahn G, Park E, Lee WW, Hyun JW, Lee KW, Shin TK, Jeon YJ, Park JW, Jee Y. Enzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathway. Mar. Biotechnol (NY). 13(1):66-73. 2011. 5. Ahn G, Park E, Park HJ, Jeon YJ, Lee J, Park JW, Jee Y. The classical NFkB pathway is required for phloroglucinol-induced activation of murine lymphocytes. Biochimica et Biophysica Acta - General Subjects. 1800 (7): 639-645. 2010. 6. Ahn G (co-first), Park E, Yun JS, Kim JM, Bing SJ, Kim DS, Lee J, Lee NH, Park JW, Lee YJ, Dieckol rescues mice from lethal irradiation by accelerating hemopoiesis and curtailing immunosuppression. International Journal of Radiation Biology. 86 (10): 848-859. 2010. 7. Ahn G, Park E, Lee WW, Hyun JW, Lee KW, Shin TK, Jeon YJ, Park JW, Jee Y. Enzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathway. Mar. Biotechnol (NY). 13 (1): 66-73. 2011. 8. Ahn G (co-first), Park SJ, Lee NH, Park JW, Jeon YJ, Jee Y. Phloroglucinol (PG) purified from Ecklonia cava attenuates radiation-induced apoptosis in blood lymphocytes and splenocytes. Food Chem Toxicol. 49 (9): 2236-2242. 2011. 9. Ahn G (co-first), Wijesinghe W. A. J. P., Lee WW, Kang MC, Kim EA, Jeon YJ. Anti-inflammatory activity of phlorotannin-rich fermented Ecklonia cava processing by-product extract in lipopolysaccharide-stimulated RAW 264.7 Macrophages. J Appl Phycol. In press (DOI 10.1007/s10811-012-9939-5). 10. Ahn G, Bing SJ, Kang SM, Lee WW, Lee SH, Matsuda H, Tanaka A, Cho IH, Jeon YJ, Jee Y. The JNK/NFκB pathway is required to activate murine lymphocytes induced by a sulfated polysaccharide from Ecklonia cava. Biochim Biophys Acta. 1830(3): 2820-2829. 2013. [국외논문 (SCI (E)급) (etc.)] 1. Park E, Lee NH, Ahn G, Baik JS, Jeon YJ, Joo HG, Lee J, Jee Y. Inhibition of Apoptosis by Elaeocarpus sylvestris in Mice following Whole-Body Exposure to Ionizing Radiation: Implications in Radioprotector. Food Sci. Biotechnol. 17 (4): 718-722. 2008. 2. Park E, Ahn G, Lee NH, Kim JM, Yun JS, Hyun JW, Jeon Y-J, Wie MB, Lee YJ, Park JW, Jee Y. Radioprotective properties of eckol against ionizing radiation in mice. FEBS Lett. 582 (6): 925-930. 2008. 3. Yasantha Athukorala, Ahn G, Jee Y, Kim GY, Kim SH, Ha, JH, Kang JS, Lee KW, Jeon YJ. Antiproliferative activity of sulfated polysaccharide isolated from an enzymatic digest of Ecklonia cava on the U-937 cell line. J Appl Phycol. 21: 307-314. 2009. 4. Bing SJ, Kim MJ, Park E, Ahn G, Kim DS, Ko RK, Lee NH, Shin T, Park JW, Jee Y. Modulation of radiation-induced apoptosis by 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) in murine splenocytes, Biol. Pharm. Bull. 33 (7): 1122-1127. 2010. 5. Heo SJ, Yoon WJ, Kim KN, Ahn G, Kang SM, Kang DH, Affan A, Oh C, Jung WK, Jeon YJ. Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages. Food Chem. Toxicol. 48: 2045-2051. 2010. 6. Kim KN, Heo SJ, Yoon WJ, Kang SM, Ahn G, Yi TH, Jeon YJ. Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages. Eur J Pharmacol. 649 (1-3): 369-375. 2010. 7. Lee SH, Ko SC, Kang SM, Cha SH, Ahn G, Um BH, Jeon YJ. Antioxidant effect of Ecklonia cava Dried by Far infrared Radiation Drying, Food Sci Biotechnol. 19 (1): 129-135. 2010. 8. Kim KN, Heo SJ, Kang SM, Ahn G, Jeon YJ. Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway. Toxicol In Vitro. 24 (6): 1648-1654. 2010. 9. Hwang I, Ahn G, Park E, Ha D, Song JY, Jee Y. An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells. Immunol Lett. 138 (2): 169-178. 2011. 10. Hwang I, Ha D, Ahn G, Park E, Joo H, Jee Y. Experimental autoimmune encephalomyelitis: Association with mutual regulation of RelA (p65)/NF-κB and phospho-IκB in the CNS. Biochem Biophys Res Commun. 411 (2): 464-470. 2011. 11. Lee W, Ahn G, Arachchillage JP, Kim YM, Kim SK, Lee BJ, Jeon YJ. A polysaccharide isolated from Ecklonia cava fermented by Lactobacillus brevisinhibits the inflammatory response by suppressing the activation of nuclear factor-κB in lipopolysaccharide-induced RAW 264.7 macrophages. J Med Food. 14 (12): 1546-1553. 2011. 12. Matsuda A, Tanaka A, Pan W, Okamoto N, Oida K, Kingyo N, Amagai Y, Xia Y, Jang H, Nishikawa S, Kajiwara N, Ahn G, Ohmori K, Matsuda H. Supplementation of the fermented soy product ImmuBalance™ effectively reduces itching behavior of atopic NC/Tnd mice. J Dermatol Sci. 67 (2): 130-139. 2012. 13. Kang MC, Ahn G, Yang X, Kim KN, Kang SM, Lee SH, Ko SC, Ko JY, Kim D, Kim YT, Jee Y, Park SJ, Jeon YJ. Hepatoprotective effects of dieckol-rich phlorotannins from Ecklonia cava, a brown seaweed, against ethanol induced liver damage in BALB/c mice. Food Chem Toxicol. 50 (6): 1986-1991. 2012. 14. Ha D, Joo H, Ahn G, Kim MJ, Bing SJ, An S, Kim H, Kang KG, Lim YK, Jee Y. Jeju ground water containing vanadium induced immune activation on splenocytes of low dose γ-rays-irradiated mice. Food Chem Toxicol. 50 (6): 2097-2105. 2012. 15. Heo SJ, Cha SH, Kim KN, Lee SH, Ahn G, Kang DH, Oh C, Choi YU, Affan A, Kim D, Jeon YJ. Neuroprotective effect of phlorotannin isolated from Ishige okamurae against H2O2-induced oxidative stress in murine hippocampal neuronal cells, HT22. Appl Biochem Biotechnol. 166 (6): 1520-1532. 2012. 16. Lee SH, Ko CI, Ahn G, You S, Kim JS, Heu MS, Kim J, Jee Y, Jeon YJ. Molecular characteristics and anti-inflammatory activity of the fucoidan extracted from Ecklonia cava. Carbohydr. Polym. 89: 599-606. 2012. 17. Ha D, Bing SJ, Cho J, Ahn G, Kim DS, Al-Amin M, Park SJ, Jee Y. Phloroglucinol protects small intestines of mice from ionizing radiation by regulating apoptosis-related molecules: a comparative immunohistochemical study. J Histochem Cytochem. 61 (1): 63-74. 2013. 18. Kim KN, Ahn G, Heo SJ, Kang SM, Kang MC, Yang HM, Kim D, Roh SW, Kim SK, Jeon BT, Park PJ, Jung WK, Jeon YJ. Inhibition of tumor growth in vitro and in vivo by fucoxanthin against melanoma B16F10 cells. Environ Toxicol Pharmacol. 35 (1): 39-46. 2013. 19. Lee W, Ahn G, Lee BJ, Wijesinghe WA, Kim D, Yang H, Kim YM, Park SJ, Jee Y, Jeon YJ. Radio-protective effect of polysaccharides isolated from Lactobacillus brevis-fermented Ecklonia cava. Int J Biol Macromol. 52: 260-266. 2013.20. Tanaka A, Jung K, Matsuda A, Jang H, Kajiwara N, Amagai Y, Oida K, Ahn G, Ohmori K, Kang KG, Matsuda H. Daily intake of Jeju groundwater improves the skin condition of the model mouse for human atopic dermatitis. J Dermatol. 40(3): 193-200. 2013. [국내 논문 (First or Second Author)] 1. Ahn YS, Lee WW, Lee SH, Ahn GN, Ko CI, Oh CK, Oh MC. Kim DW. Jeon YJ, Kim SH. Processing and Biological Activity of Gelatin Hydrolysate from Branchiostegus japonicus Scales. Kor J Fish Aquat Sci. 42(50): 417-425 (2009) 2. Ahn YS, Lee WW, Lee SH, Ahn GN, Ko CI, Oh CK, Oh MC, Kim DW. Jeon YJ, Kim SH. Angiotensin 1 Converting Enzyme Inhibitory Effects of Gelatin Hydrolysates Prepared from Tilapia mossambica Scales by Hot Water and Enzymatic Extraction. . Kor J Fish Aquat Sci. 42(5): 426-433 (2009) 3. Ahn G, Kim MJ, Kim DS, Lee NH, Shin TK, Park JW, Jeon YJ, Lee KW, Jee Y. Inhibitory effect of phloroglucinol against the expression of p63 protein in jejunal of ?-ray irradiated mice. Journal of Applied Rediological Science Research Institute. 2010 4. Ko SC, Kang SM, Lee SH, Ahn G, Kim KN, Kim YT, Lim JS, Heu MS, Jeon Y-J. Protective Effect of Enzymatic Extracts from Sargassum coreanum on H2O2-induced Cell Damage. Fish Aqua Sci. 13(1): 26-35 (2010) 5. 고석천, 강성명, 안긴내, 양현필, 김길남, 전유진, 큰잎모자반 효소적 추출물의 항산화 활성, 한국식품영양과학학회지: 39(4),494-499 (2010).6. Dae Seung Kim, Insun Hwang, Suk-jae Park, Ginnae Ahn, Sang-Joon Park, Hyun Jeong Park, Hong-Gu Joo, Youngheun Jee. Overexpression of Galectin-3 in macrophages of C57BL/6 mice with Experimental autoimmune encephalomyelitis. 대한수의학회지. 51(2): 139-149 (2011) Profile Name : Ahn, Ginnae Professor's classification : Professor Final academic degree : Ph.D. in Science Major & Research : Marine Life Sciences, Aquatic food materials and functions E-mail : gnahn@jnu.ac.kr TEL : +82-61-659-7213 대표 강의 교과목 - 수산과학개론 - 수산식품냉동학 - 수산식품소재학 - 해양바이오소재 세미나 - 동물세포배양학 및 실험 - 수산부산물이용학 - 바이오식품전공영어 - 해양천연물화학